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Women with a history of eating disorders, gastrointestinal conditions such as gastroparesis, or those who are nutritionally vulnerable should exercise particular caution

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Discussion This study found that use of GLP-1 agonists for weight loss compared with use of bupropion-naltrexone was associated with increased risk of pancreatitis, gastroparesis, and bowel obstruction but not biliary disease

6 mg/week in Months 79 , and 812 mg/week in Months 1012 for maximum-efficacy cases

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Compounding is regulated under FD&C Act Section 503A